Nerve Blocks for Headaches: What to Expect from an Interventional Approach

Published: July 22, 2026

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Summary: A headache nerve block involves injecting a local anesthetic, often with a corticosteroid, around a specific nerve that transmits pain signals to the head. Beyond providing relief, a nerve block serves a diagnostic purpose: how your pain responds tells your physician where it’s actually originating. Blocks work particularly well for occipital neuralgia, cervicogenic headache, and chronic migraine with a neck component, and relief often outlasts the anesthetic itself by weeks or longer. This is a core part of interventional pain management at MAPS, and one many headache patients have never had explained to them.

If your headache treatment history consists entirely of medications, there’s an option you may not have heard about. Nerve blocks are a mainstay of interventional headache care, and for the right patient, they can do something no pill can: tell you exactly where your pain is coming from while relieving it at the same time. Here’s how they work and what the experience is actually like.

What a Headache Nerve Block Is

Which Nerves Are Targeted and Why

The most common headache nerve block targets the occipital nerves, which run from the top of the neck up the back of the head. These nerves are frequently involved in headache pain, and they also share pathways with the trigeminal system involved in migraine, which is part of why blocking them can affect migraine pain rather than only pain at the back of the head. Depending on your symptoms, other targets may include the supraorbital, supratrochlear, or auriculotemporal nerves.

How a Nerve Block Differs From a Pain Injection

The distinction is about what’s being targeted. A trigger point injection treats a specific tight, painful spot within a muscle. A nerve block delivers medication around a nerve itself to interrupt the transmission of pain signals along that pathway. Both have their place, but they address fundamentally different mechanisms.

The Dual Purpose: Diagnostic and Therapeutic

This is what makes nerve blocks genuinely different from most headache treatments, and it’s central to how MAPS approaches diagnosis.

What Your Response to a Block Tells Your Doctor

If numbing a specific nerve substantially relieves your headache, that’s direct evidence about where your pain originates, not an inference drawn from symptom descriptions or imaging. If it doesn’t help, that’s useful information too, ruling out that pathway and redirecting the investigation. Few headache treatments provide that kind of clarity, which is why blocks are often used early rather than as a last resort.

Why Relief Can Outlast the Anesthetic Itself

The local anesthetic wears off within hours, yet many patients experience relief lasting weeks or months. The likely explanation is that interrupting sustained pain signaling gives a sensitized nervous system a chance to reset. When a corticosteroid is included, it reduces inflammation around the nerve as well, extending the benefit further.

Who Nerve Blocks Work Best For

Occipital Neuralgia and Cervicogenic Headache

These are the clearest indications. Occipital neuralgia involves direct irritation of the occipital nerves, producing sharp, shooting pain at the back of the head. Cervicogenic headache originates from structures in the neck and refers pain into the head. Both respond well because the block targets the actual source.

Chronic Migraine With a Neck Component

A meaningful number of chronic migraine patients have an unrecognized cervical contributor feeding their pattern. For these patients, occipital nerve blocks can address a piece of the problem that oral migraine medication was never going to reach, often used alongside Botox or preventive medication rather than instead of them.

Patients Who Can’t Tolerate Daily Preventive Medication

For patients who’ve had difficulty with side effects from oral preventives, or who are pregnant or have other reasons to avoid systemic medication, nerve blocks offer a targeted, localized alternative that doesn’t require taking something every day.

What the Procedure Actually Involves

Session Length, What You Feel, and Same-Day Recovery

The procedure itself takes only a few minutes. You’ll typically be seated or lying down while the injection site is cleaned, and most patients describe the injection as a brief sting followed by a spreading numbness or pressure at the back of the head. There’s no sedation involved, and you can drive yourself home afterward. Some patients feel relief almost immediately; others notice it building over the following days as any corticosteroid takes effect.

Mild tenderness at the injection site for a day or two is common and expected. Temporary numbness across part of the scalp is also normal and resolves as the anesthetic wears off.

How Long Relief Typically Lasts and When Blocks Are Repeated

Duration varies considerably, from a few weeks to several months, depending on your underlying condition and whether a steroid was included. Blocks can be repeated at appropriate intervals, and for patients who respond well but see relief fade predictably, a repeating schedule often becomes part of their ongoing plan.

Where Nerve Blocks Fit Alongside Other Treatments

Nerve blocks aren’t usually meant to be a standalone solution. They work best within a broader plan, providing diagnostic clarity that shapes the rest of your treatment, offering bridge relief while a preventive medication or Botox regimen takes effect, or addressing a cervical contributor alongside migraine-specific treatment. Our full root-cause approach explains how these components get sequenced based on what your evaluation finds.

Explore Interventional Headache Treatment at MAPS

If your headache treatment has been limited to medication and you’re still struggling, an interventional evaluation may reveal options you didn’t know existed, along with answers about where your pain is actually coming from. Our double board-certified, fellowship-trained physicians perform these procedures regularly as part of a comprehensive, non-opioid approach to headache care. Schedule a consultation with MAPS Centers for Pain Control at any of our 8 Chicagoland locations.

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